Friday, May 4

Insights from completed/ongoing EVT acute stroke RCTs

15 minute talks followed by 5 minutes of discussion

Moderators: M Goyal, M Hill

1300-1310 Welcome/IntroductionM Goyal
1310-1330 HERMES highlights M Goyal
1330-1350 Tissue and Time: EVT trials DAWN/ DEFUSE-3 trials B Menon
1350-1410 Tissue and Time: Intravenous thrombolysis trials J Grotta
1410-1430 MR CLEAN new trialsA van der Lugt
1430-1500 Coffee Break

Future clinical trials

A case vignette will be presented and an interactive audience polling system will be used. Each speaker will present an argument for a trial. The topic will then be open to polling again for management. Before and after polling results will be presented and the forum opened to general discussion.
1500-1510 Case presentation #1
1510-1525 Extending boundaries for EVT (low ASPECTS) J Fiehler
1530-1540 Case presentation #2
1540-1555 Extending boundaries for EVT (low NIHSS) A Demchuk
1600-1610 Case presentation #3
1610-1625 Extending boundaries for EVT (distal occlusion trials) B Menon
1630-1645 Making sense of it all: Individualized treatment decision in acute stroke
U Fischer
1645-1700 Areas for future RCTs/Q &A
1800-1930 Cocktails and social hour
1930-2130 Dinner

Saturday, May 5

Strokes of A Clock

Challenges, solutions and innovations from first contact to endovascular therapy and beyond

Workflow and process oriented sessions will focus on each interval step leading up to EVT administration and subsequent medical care. At the beginning of each session, an exemplar case vignette will be presented that highlights a decision-making problem. Invited speakers will present their views on the problem and offer solutions. Technology/innovations in the field of each interval step will be highlighted where applicable. The session will then be open to the audience for discussion.
0800-0835 Session 1: Decision-making in the field
Moderators: A. Alexandrov, M Jayaraman
0800-0810 Mobile stroke units J Grotta
0810-0820 Optimal triaging algorithmsJ Holodinsky
0820-0823 Technology: Cerebrotech visor N Kamal
0823-0826 Technology: Cerebrotech visorM Goyal
0826-0829 Technology: NeuroAnalytics A Demchuk
0829-0835 Q and A
0835-0910 Session 2: Patient arrived at the primary stroke centre first
0835-0843 Imaging at the PSC M Almekhlafi
0843-0851 Fast DIDO: How to do it? R McTaggart
0851-0900Echnology: CLOTBUST 2 TrialA Alexandrov
0900-0910 Q and A
0910-0940 Session 3: Imaging at the CSC
0910-0918 Onset to imaging < 6 hours A van der Lugt
0918-0926 Onset to Imaging > 6 hours D Dowlatshahi
0926-0934 Technology: Direct to angioM Psychogios
0934-0940 Q and A
0940-1010 Session 4: Medical treatments before EVT
0940-0948 tPA Bridging YES: Give the juice! M Hill
0948-0956 tPA Bridging NO: It rarely works! U Fischer
0956-1002 Technology: Tenecteplase (TNK-tPA) and other thrombolytic drugsS Coutts
1002-1010 Q and A
1010-1030Coffee Break
1030-1110 Session 5: In the angio suite – how to move quickly but safely
Moderator: M Goyal
1030-1038 GA versus no sedation? W Brinjikji
1038-1046 Speeding up puncture to reperfusion time M Poitin
1046-1102 Technology: Distal emboli prevention M Gounis
1102-1110 Q and A
1110-1155 Session 6: In the angio suite – difficult to open cases
1110-1125 What to do when it does not want to open M Poitin
1125-1140 Technology: Future solutions for that difficult to open arteries M Gounis
1140-1155 M1 occlusion turned to be on top of atherosclerotic disease: What to do? TBD
1155-1210 Carotid stenosis: When to revascularize/antithrombotic management? D Heck
1210-1225 UNMASK-EVT study resultsTBD
1225-1235Q and A
1235-1335 Lunch
1300-1500 ESCAPE-NA1 & TEMPO-2 trials meeting (Trials centres only)
1800-2000Dinner & Speaker

Sunday, May 6

Decision Court

These sessions focus on challenging decisions that physicians face. Each expert will present a major challenge/complication that they have encountered. Other experts will constitute a judge and jury bench that will discuss medical issues around these complications. Audience opinion will be sought using qualitative interactions and opinion polls.
0800-0845 Scenario 1: Older patient at a PSC with high NIHSS and moderate ASPECTS, with proximal occlusion and did not transfer
Judges: A Alexandrov, J Grotta
Lawyers: R McTaggart, M Hill
0845-0930 Scenario 2: “Difficult vascular access and I gave up”
Judges: J Wong, V Mendes Pereira
Lawyers: J Fiehler, D Heck
0930-1000 Coffee Break
1000-1045 Scenario 3: Dominant M2 branch occlusion with NIHSS 12 — “I treated with IV tPA and did not refer to EVT”
Judges: A Demchuk, A van der Lugt
Lawyers: B Menon, A Alexandrov
1045- 1130 Scenario 4: Patient with M1 occlusion but NIHSS only 3: Neurologist did not refer for EVT
Judge: M Goyal
Lawyer: A Demchuk
1130-1215 Scenario 5: Young patient with early presentation and good collateral — “Tried to open the artery for 2 hours then gave up at < 6 hours from onset”
Judge:M Goyal
Lawyers: TBD
1215-1230Q &A & Thanks

Bon Voyage!